Fig. 1: Local irradiation promotes lung metastasis of 4T1 cells. | Cell Death & Disease

Fig. 1: Local irradiation promotes lung metastasis of 4T1 cells.

From: Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells

Fig. 1

a, b BALB/c mice were subcutaneously injected with 4T1 cells (4 × 105), 10 days later the tumor sites were irradiated (4 Gy) with X-ray. The tumor volume (a) and metastatic nodules (b) were recorded after 30 days. n = 4 for each group. c BALB/c mice were whole-body irradiated (4 Gy), but with the thorax shielded (WBI-T), and 4T1 cells (5 × 104) were injected via tail vein within 24 h. Metastatic nodules were counted after 14 days. n = 3 for each group. All experiments in this figure were repeated at least three times. **p < 0.01.

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