Fig. 2: Treatment with 2-Cl-IB-MECA does not change a-wave and b-wave amplitudes. | Cell Death & Disease

Fig. 2: Treatment with 2-Cl-IB-MECA does not change a-wave and b-wave amplitudes.

From: Activation of adenosine A3 receptor protects retinal ganglion cells from degeneration induced by ocular hypertension

Fig. 2

Saline (5 µl) or 2-Cl-IB-MECA (5 µl, 1.2 µM) was administered by intravitreal injection immediately after laser-induced OHT, and at day 6 after OHT induction the ERG was recorded. a Representative traces of scotopic a- and b-wave amplitude and photopic b-wave at 2.19 log cd·s/m2. b, c Scotopic a- and b-wave amplitudes recorded at different light intensities. d Photopic b-wave amplitudes recorded at 2.19 log cd·s/m2. Results presented were obtained from 5–6 animals. +p < 0.05, ++p < 0.01, +++p < 0.001, ++++p < 0.0001, significantly different from naïve; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, significantly different from contralateral eye; and #p < 0.05, ##p < 0.01, significantly different from saline-treated OHT.

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