Fig. 6: TDO2 promotes the progression of HCC cell lines.

a, b Relative expression of TDO2 in Huh7 and LM3 cells transfected with shTDO2, TDO2, or NC was detected by qRT-PCR and WB. c, d The effects of TDO2 on HCC cells migration, invasion, and proliferation were evaluated by the transwell migration and invasion assays, the colony formation assay and the CCK-8 assay. All data are from three independent experiments and are presented as the means ± SEM or representative of three independent experiments with similar results (*p < 0.05, **p < 0.01, ***p < 0.001).