Table 3 Correlation between clinicopathologic features and the expression of TDO in 57 cases of HCC tissues (n = 57, χ2-test).

From: Circular RNA circZNF566 promotes hepatocellular carcinoma progression by sponging miR-4738-3p and regulating TDO2 expression

 

N

TDO2

Expression

P-value

  

High (%)

Low (%)

 

Age (year)

   

0.258

 <60

45

32 (71.1%)

13 (28.9%)

 

 ≥60

12

11 (91.7%)

1 (8.3%)

 

Gender

   

0.261

 Male

46

33 (71.7%)

13 (90.9%)

 

 Female

11

10 (28.3%)

1 (9.1%)

 

Tumor number

   

0.664

 Single

49

36 (73.5%)

13 (26.5%)

 

 Multiple

8

7 (87.5%)

1 (12.5%)

 

Tumor size

   

0.002

 <5 cm

27

15 (55.6%)

12 (44.4%)

 

 ≥5 cm

30

28 (93.3%)

2 (6.7%)

 

Tumor differentiation

   

0.012

 I–II

37

24 (64.9%)

13 (35.1%)

 

 III–IV

20

19 (95.0%)

1 (5.0%)

 

Tumor location

   

0.054

 Left liver

10

5 (50.0%)

5 (50.0%)

 

 Right liver

42

34 (81.0%)

8 (19.0%)

 

 Whole liver

5

4 (100.0%)

1 (0.0%)

 

Vascular invasion

   

0.083

 Yes

16

15 (93.8%)

1 (6.3%)

 

 No

41

28 (68.3%)

13 (31.7%)

 

Liver cirrhosis

   

0.358

 Yes

29

20 (69.0%)

9 (31.0%)

 

 No

28

23 (82.1%)

5 (17.9%)

 

Hepatitis virus

   

0.629

 Yes

6

4 (66.7%)

2 (33.3%)

 

 No

51

39 (76.5%)

12 (23.5%)

 

M stage

   

0.049

 M0

46

32 (69.6%)

14 (32.4%)

 

 M1

11

11 (100%)

0 (0%)