Table 2 The clinical information of normal controls and patients with COVID-19 pneumonia.

From: The inhibition of IL-2/IL-2R gives rise to CD8+ T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia

 

Normal controls

(n = 16)

Common patients

(n = 34)

Severe patients

(n = 14)

Critical patients

(n = 6)

P value

Ages (years old)

55 ± 13

50 ± 15

63 ± 5

75 ± 10

−

Gender(male/female)

6/10

14/20

6/8

2/4

−

White blood cell (×109/L)

6.46 ± 0.36

4.02 ± 0.23

7.36 ± 0.76

8.39 ± 1.38

0.000

Neutrophil (×109/L)

3.61 ± 0.25

2.47 ± 0.21

5.41 ± 0.71

7.57 ± 1.26

0.000

Lymphocyte (×109/L)

2.36 ± 0.14

1.13 ± 0.08

1.22 ± 0.24

0.41 ± 0.11

0.000

Monocyte (×109/L)

0.36 ± 0.02

0.25 ± 0.02

0.49 ± 0.11

0.26 ± 0.06

0.005

Neutrophil (%)

55.18 ± 1.63

60.07 ± 2.02

71.24 ± 4.03

89.38 ± 1.99

0.000

Lymphocyte (%)

34.86 ± 2.56

29.11 ± 1.95

17.98 ± 3.07

5.54 ± 1.18

0.000

Monocyte (%)

5.72 ± 0.47

6.37 ± 0.33

7.01 ± 1.58

3.18 ± 0.47

0.082

Alanine aminotransferase (U/L)

19.85 ± 2.33

49.53 ± 9.8

49.29 ± 9.1

49.17 ± 15.06

0.232

Aspartate aminotransferase (U/L)

22.23 ± 1.71

38.53 ± 5.41

39.14 ± 5.79

85.17 ± 31.05

0.003

Total bilirubin (μmol/L)

14.71 ± 1.29

9.73 ± 0.56

11.29 ± 2.16

18.40 ± 2.24

0.000

Direct bilirubin (μmol/L)

4.67 ± 0.47

1.91 ± 0.12

3.79 ± 1.81

6.52 ± 1.58

0.006

Total protein (g/L)

74.93 ± 1.02

73.52 ± 0.92

71.69 ± 2.02

69.52 ± 3.64

0.241

Albumin (g/L)

46.1 ± 0.54

36.70 ± 0.71

31.05 ± 0.96

30.70 ± 1.88

0.000

Creatinine (μmol/L)

56.19 ± 2.92

59.94 ± 2.76

56.43 ± 3.66

96.83 ± 25.72

0.002

Glomerular filtration rate (mL/min/1.73 m2)

126.59 ± 5.62

113.32 ± 5.62

101.19 ± 3.47

70.85 ± 14.15

0.000

Procalcitonin (ng/mL)

0.10 ± 0.001

0.13 ± 0.004

0.18 ± 0.04

3.42 ± 3.15

0.015

C reactive protein (mg/L)

2.50 ± 0.25

16.50 ± 2.73

46.34 ± 9.82

96.73 ± 21.72

0.000

Saturation of oxygen (%)

98.53 ± 1.21

96.83 ± 0.90

92.84 ± 0.59

87.03 ± 2.95

0.019