Fig. 5: ANRIL binds with NOX1 promoter region and actives its expression. | Cell Death & Disease

Fig. 5: ANRIL binds with NOX1 promoter region and actives its expression.

From: LncRNA ANRIL acts as a modular scaffold of WDR5 and HDAC3 complexes and promotes alteration of the vascular smooth muscle cell phenotype

Fig. 5

a, b mRNA a and protein b levels of NOX1 and NOX4 in HASMCs with ox-LDL inducing and ANRIL overexpressing or silencing. c Dual-luciferase activity assay in which ox-LDL induced HASMCs were transfected with NOX1 gene promoter plasmid and ANRIL overexpressing or silencing plasmids. d Correction analysis of ANRIL and NOX1 expression levels as measured in PBMCs from CAD subjects (n = 45).

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