Fig. 4: Involvement of IKKβ in CRYAB commanding canonical NF-κB pathway. | Cell Death & Disease

Fig. 4: Involvement of IKKβ in CRYAB commanding canonical NF-κB pathway.

From: Inhibition of miR-450b-5p ameliorates hepatic ischemia/reperfusion injury via targeting CRYAB

Fig. 4

a, b Immunofluorescence of p-IKKβ-F4/80 and p-IKKα-F4/80 in CRYAB knocking-down or IMD0354-utilized groups. Scale bar = 50 μm. c, d, f, g Impact of IMD0354 upon canonical and noncanonical NF-κB protein within CRYAB abrogation. e Levels of IL-6, IL-1β, and TNF-α in cell supernatant. *P < 0.05, **P < 0.01, nsP > 0.05.

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