Fig. 2: The expression level of POU4F1 was associated with Ki-67 level and the progression of melanoma. | Cell Death & Disease

Fig. 2: The expression level of POU4F1 was associated with Ki-67 level and the progression of melanoma.

From: POU4F1 promotes the resistance of melanoma to BRAF inhibitors through MEK/ERK pathway activation and MITF up-regulation

Fig. 2

a Representative immunohistochemistry staining images of Ki-67 and POU4F1 expressions in nevus and melanoma tissues, bar = 200 μm. b Quantitative analysis of Ki-67 staining score. c Quantitative analysis of POU4F1 staining score. (nevus n = 6, primary melanoma n = 10, metastatic melanoma n = 10) Data are mean ± SEM, **p < 0.01, ***p < 0.001.

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