Table 3 The clinical characteristics of patients according to the expression of DAXX in cytoplasm and nuclear.

Variables	Expression of DAXX in cytoplasm		P value	Expression of DAXX in nuclear		P value
	High (n = 147)	Low (n = 176)		High (n = 183)	Low (n = 140)
Gender, n (%)			0.412			0.188
Male	108	122		125	105
Female	39	54		58	35
Age (years), n (%)			0.917			0.727
<60	68	83		84	67
≥60	78	93		99	73
Tumor size (cm), n (%)			0.272			0.238
<4	75	79		82	72
≥4	73	97		101	68
Depth of invasion, n (%)			0.105			0.602
T1 + T2	56	52		59	49
T3 + T4	91	124		124	91
Lymph node metastasis, n (%)			<0.01^a			0.561
N0 + N1	94	80		96	78
N2 + N3	53	96		87	62
M stage			0.599			0.680
M0	145	171		178	138
M1	2	5		5	2
TNM stage			0.003^a			0.407
I + II	83	70		83	70
III + IV	64	106		100	70
Lauren type			<0.01^a			0.540
Intestinal	85	61		80	66
Diffuse	62	115		103	74
CEA	8.40 ± 21.60	6.50 ± 21.83	0.449	8.26 ± 22.95	6.09 ± 19.78	0.394
CA199	36.64 ± 88.87	55.28 ± 159.17	0.219	53.43 ± 150.50	36.27 ± 95.15	0.286
CA724	7.22 ± 15.93	16.89 ± 47.37	0.047	13.69 ± 36.15	9.77 ± 36.98	0.465
Chemotherapy			0.261			0.173
No	45	44		45	44
Yes	102	132		138	96
Borrmann			0.438			0.203
I	18	13		14	17
II	57	74		69	62
III	62	73		83	52
IV	10	16		17	9
Relapse			<0.01^a			<0.01^a
No	105	74		81	98
Yes	42	102		102	42

CEA carcinoembryonic antigen, CA199 carbohydrate antigen199, CA724 carbohydrate antigen724, TNM tumor node and metastasis.
^aStatistically significant (P < 0.01).

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