Fig. 2: Motor deficits in VMP1cKO mice. | Cell Death & Disease

Fig. 2: Motor deficits in VMP1cKO mice.

From: Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

Fig. 2

Total traveled distance (A), vertical time (B), vertical counts (C), stereotypic time (D), and stereotypic counts (E) were presented, respectively (N = 24 mice per genotype). F The latency to fall from rotarod was recorded from VMP1cWT and VMP1cKO mice from the 45th to 65th postnatal day (N = 23–24 mice per genotype). G The mice entered a, b, or c arm were recorded, and the Y-maze alteration rate was calculated (N = 16–20 mice per genotype). H The immobile time was recorded in the tail suspension test (N = 9–12 mice per genotype). A–F were analyzed by using two-way ANOVA followed by Sidak’s multiple comparisons test. G, H were analyzed by using Student’s t-test. Data were represented as mean ± SEM. ****p < 0.0001.

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