Fig. 6: Mitochondrial defects in the mDAergic neurons of VMP1cKO mice. | Cell Death & Disease

Fig. 6: Mitochondrial defects in the mDAergic neurons of VMP1cKO mice.

From: Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

Fig. 6

A The representative TEM images of the observed mitochondria. Scale bar, 0.5 μm. B Quantification of the mean perimeter of mitochondria (N = 3 mice per genotype). C The proportion of mitochondria with damaged cristae was quantified (N = 351 mitochondria collectively counted from 3 VMP1cWT mice, N = 291 mitochondria collectively counted from 3 VMP1cKO mice). Data were analyzed by using Student’s t-test and were represented as mean ± SEM. *p < 0.05, ****p < 0.0001. Mito mitochondria.

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