Fig. 3: Subcutaneous tumor formation in nude mice confirmed that silencing SNHG1 inhibited the proliferation of PCa cells in vivo.

A, B Negative control or sh-SNHG1was stably transfected into DU145 cells, which were injected into the nude mice. C Tumor volumes were calculated after injection every 4 days. D Tumor weights were represented as means of tumor weights ± SD. E IHC analyses of ki-67 confirmed that the proliferation of subcutaneous tumor was inhibited in sh-SNHG1 group. ***P < 0.001, ****P < 0.0001.