Fig. 6: Tan IIA suppresses the in vivo tumor growth of OSCC cells.
From: Targeting Aurora B kinase with Tanshinone IIA suppresses tumor growth and overcomes radioresistance
A–C The tumor volume (A), the image of tumor mass (B), and tumor weight (C) of CAL27-derived xenograft tumors treated with vehicle or Tan IIA; n = 5 mice per group, one-way ANOVA. ***p < 0.001. D–F The tumor volume (D), The image of tumor mass (E), and tumor weight (F) of SCC25-derived xenograft tumors treated with vehicle or Tan IIA; n = 5 mice per group, one-way ANOVA.***p < 0.001. For B and E, scale bar, 1 cm. G IHC staining of Ki67 and p-Histone H3 Ser10 in CAL27-derived xenograft tumors with vehicle or Tan IIA treatment. Scale bar, 25 μm. H Qualification analysis of p-Histone H3 Ser10 and Ki67 in CAL27-derived xenograft tumors with vehicle or Tan IIA treatment; one-way ANOVA, ***p < 0.001.
