Fig. 5: CD127+ M-MDSCs induced by CHBP exerted stronger immunosuppressive function.
From: CHBP induces stronger immunosuppressive CD127+ M-MDSC via erythropoietin receptor
A RNA-seq detected the different RNA expressions in M-MDSCs with or without CHBP treatment in vitro. B The String analysis of mRNA sequencing. C The Jak2 and GATA3 protein expression by western blot. D The p-STAT3 and STAT3 protein expression by western blot. E Protein array compared the difference in M-MDSCs with or without CHBP treatment in vitro. F The molecular function enrichment of protein array. G Detection and quantification of the CD127-positive cells in M-MDSCs by flow cytometry. H T-cell proliferation detected by CFSE. The ratio of G-MDSCs and T cells was 1:1.
