Table 2 Kidney function parameters in animal model.

From: Characterization of ferroptosis in kidney tubular cell death under diabetic conditions

 

Con

Con + Fer-1

STZ

STZ + Fer-1

Body weight, g

30.32 ± 3.61

29.33 ± 1.54

22.33 ± 1.73

26.81 ± 2.71

Kidney weight, mg

188.40 ± 12.23

177.55 ± 7.65

197.05 ± 14.41

186.10 ± 11.49

Kidney/body weight, 10−3

6.28 ± 0.62

6.07 ± 0.43

8.84 ± 0.40

6.98 ± 0.46

Blood glucose, mg/dl

126.20 ± 17.50

114.70 ± 18.87

524.00 ± 84.18

515.70 ± 94.51

Serum creatinine, mg/dl

0.15 ± 0.04

0.13 ± 0.02

0.24 ± 0.09

0.20 ± 0.04

Serum BUN, mg/dl

24.92 ± 2.42

23.00 ± 1.17

29.26 ± 2.80

26.90 ± 4.12

UACR, µg/mg

0.015 ± 0.004

0.013 ± 0.001

0.053 ± 0.017

0.033 ± 0.010

  1. Data are shown as mean ± standard deviation.
  2. Con control, Fer-1 ferrostatin-1, DM diabetes mellitus, BUN blood urea nitrogen, UACR urine albumin to creatinine ratio.
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