Fig. 5: Regulation of miR-483-5p on the renal interstitial fibrosis in type 1 and type 2 diabetic mice. | Cell Death & Disease

Fig. 5: Regulation of miR-483-5p on the renal interstitial fibrosis in type 1 and type 2 diabetic mice.

From: HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis

Fig. 5

A–D Detection of serum creatinine and urinary albumin to creatinine ratio concentrations by Creatinine Serum Detection Kit and urinary albumin to creatinine ratio assay kit. E–H Detection of TIMP2, ERK1/2, and miR-483-5p expressions by qRT-PCR and western blot. *P < 0.05, **P < 0.01 vs. control or db/m. #P < 0.05, ##P < 0.01 vs. STZ + AAV-control or db/db + AAV-control. One-way ANOVA followed by Tukey’s or LSD post-test. STZ Streptozotocin, db/m db/misty, ACR albumin to creatinine ratio.

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