Fig. 1: Piezo1 expression in normal skin and HS tissues. | Cell Death & Disease

Fig. 1: Piezo1 expression in normal skin and HS tissues.

From: Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1

Fig. 1

A The relative expression of Piezo1 and Piezo2 mRNA from HDFs was analyzed by real-time RT-PCR. B, C Images and quantitative analysis of Piezo1 in human normal skin and HS. (Scale bar = 50 μm). The basal epithelial layer was excluded from quantitation. D Images of immunofluorescence co-staining of Piezo1 and α-SMA in human normal skin and HS. Piezo1 are labeled in red and α-SMA in green. (Scale bar = 100 μm). Scale bars for the zoom images, 20 µm. E, F Images and quantitative analysis of immunohistochemistry staining of Piezo1 in rat normal skin and HS. (Scale bar = 50 μm). The basal epithelial layer was excluded from quantitation. G Images of immunofluorescence co-staining of Piezo1 and α-SMA in rat normal skin and HS. Piezo1 are labeled in red and α-SMA in green. (Scale bar = 100 μm). Scale bars for the zoom images, 20 µm. The arrowheads point to the fibroblasts. The results are expressed as the means with SD (n = 3). The T-test is used for all analysis. ***P < 0.005.

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