Fig. 4: Ring1b complexes promote invasion in breast cells.

Proteins as indicated were stably overexpressed or knocked down in cells using lentivirus. A–D Effect of Ring1b complexes on cell invasion in 10 A and 231 cells. Statistical analysis for cells migration and invasion by Transwell assays are presented in the bar graphs. Scale bar, 60 μm. Error bars represent the means ± SEM. Unpaired t-test is performed to indicate a statistically significant difference. ***P < 0.001.