Fig. 4: Dendritic spine density is maintained in the hippocampus of old CTC KI/Cre mice. | Cell Death & Disease

Fig. 4: Dendritic spine density is maintained in the hippocampus of old CTC KI/Cre mice.

From: Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits

Fig. 4

a Representative micrographs of Golgi-cox staining and b quantification of dendritic spine density in hippocampal CA1 sections from 25-month-old CTC KI/Cre (n = 3), CTO KI/Cre (n = 5), CTC KI/WT (n = 4), CTO KI/WT (n = 4), WT/Cre (n = 5), and WT/WT (n = 4). WC: WT/Cre, WW: WT/WT. Data represent the mean ± SEM. One-way ANOVA followed by Bonferroni’s post-hoc.

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