Fig. 3: SDF-1 triggers CAF-induced EMT and invasion in lung cancer cells. | Cell Death & Disease

Fig. 3: SDF-1 triggers CAF-induced EMT and invasion in lung cancer cells.

From: Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling

Fig. 3

a, b SDF-1 protein levels in the conditioned medium quantified by ELISA. a Five groups of CAF and corresponding NF cultured separately for 72 h. b Lung cancers cells incubated with DMEM, NF-CM, CAF-CM, and CAF-CM + SDF-1 neutralising antibody for 24 h. c Western blotting analysis of epithelial and mesenchymal marker expression. d Transwell assay examining the invasiveness of cells; scale bar: 200μm.The error bars represent suggested the standard errors of the mean of the three individual experiments. *p < 0.05.

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