Fig. 7: The high expression of CXCR4, β-catenin, and PPARδ is positively correlated and predicts poor prognosis in human lung ADC. | Cell Death & Disease

Fig. 7: The high expression of CXCR4, β-catenin, and PPARδ is positively correlated and predicts poor prognosis in human lung ADC.

From: Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/β-catenin/PPARδ signalling

Fig. 7

a, c CXCR4, β-catenin, and PPARδ protein levels were evaluated in 75 human lung ADC tissues using immunohistochemical staining of tissue microarrays; scale bar: 100 μm. Case 1 and Case 2 represent two different patients. For each case, tumour and corresponding tissues were from one patient. b Kaplan–Meier analysis was used to evaluate patients’ overall survival with lung ADC and high or low expression of CXCR4, β-catenin, and PPARδ. d Analysis of the clinicopathological significance of CXCR4, β-catenin, and PPARδ protein in 75 human lung ADC tissues. e, f Pearson correlation analysis was performed to detect correlations between the expression of CXCR4, β-catenin, and PPARδ.

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