Fig. 2: Deletion of Gab2 reduces the adipose tissue weight in mice fed with HFD.

A, B Tissue weight (A) and tissue weight ratio to bodyweight (B) of Gab2 KO and WT mice fed with SD and HFD diet for 12 weeks. C–F Representative image (C), hematoxylin and eosin (H&E) staining and adipocyte area of iWAT (D), eWAT (E) and BAT (F) from Gab2 KO and WT mice fed with SD and HFD diet for 12 weeks, scale bar is 50 μm. The data are presented as mean ± SD from at least six mice in each group. Statistical difference is indicated: *P < 0.05; **P < 0.01; ***P < 0.001.