Fig. 3: Deletion of Gab2 improves glucose tolerance and insulin sensitivity in HFD-fed mice. | Cell Death & Disease

Fig. 3: Deletion of Gab2 improves glucose tolerance and insulin sensitivity in HFD-fed mice.

From: Gab2 deficiency suppresses high-fat diet-induced obesity by reducing adipose tissue inflammation and increasing brown adipose function in mice

Fig. 3

A Fasting blood glucose in Gab2 KO and WT mice fed with SD and HFD diet for 12 weeks. B, C Glucose tolerance test (GTT, B) and insulin tolerance test (ITT, C) performed in Gab2 KO and WT mice fed with SD and HFD diet for 12 weeks. Left panel, the curve of blood glucose concentration; Right panel, quantification of the area under the curve (AUC). The data are presented as mean ± SD from at least 6 mice in each group. Statistical difference is indicated: *P < 0.05; **P < 0.01.

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