Fig. 2: CPX inhibits GBM cell migration and invasion. | Cell Death & Disease

Fig. 2: CPX inhibits GBM cell migration and invasion.

From: Ciclopirox and bortezomib synergistically inhibits glioblastoma multiforme growth via simultaneously enhancing JNK/p38 MAPK and NF-κB signaling

Fig. 2

A, B Representative image of transwell migration (A) and quantitation of cell migration (B) of U251, SF126, and A172 cells. Migrated cells were stained with 0.1% crystal violet and were then imaged and quantified. Data represent mean ± SD (n = 3; ***p < 0.001). C, D Representative images of invasion (C) and quantitation of cellular invasion (D) of U251, SF126, and A172 cells. Invaded cells were stained with 0.1% crystal violet and were then imaged and quantified. Data represent mean ± SD (n = 3; *p < 0.05; **p < 0.01; ***p < 0.001). E U251, SF126, and A172 cells were treated with a range of CPX concentrations for 48 h, followed by immunoblot analysis with the indicated antibodies.

Back to article page