Fig. 6: Correlations between cytokines and metabolites before tocilizumab infusion in patients with worsening COVID-19 highlighted that dysregulated metabolomic and immunologic pathways were closely related to clinical worsening of patients developing critical COVID-19. | Cell Death & Disease

Fig. 6: Correlations between cytokines and metabolites before tocilizumab infusion in patients with worsening COVID-19 highlighted that dysregulated metabolomic and immunologic pathways were closely related to clinical worsening of patients developing critical COVID-19.

From: Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers

Fig. 6

A Correlation between cytokines and most significant metabolites at baseline was analyzed by Pearson correlation. *p < 0.05, **p < 0.01, ***p < 0.001. B Pearson correlations between IL10 and IL18 with anthranilic acid serum levels.

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