Fig. 2: Effects of CTRP12 on the expression of cholesterol efflux and uptake markers. | Cell Death & Disease

Fig. 2: Effects of CTRP12 on the expression of cholesterol efflux and uptake markers.

From: CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway

Fig. 2

A–D THP-1 macrophages were incubated with 50 µg/mL ox-LDL for 48 h, followed by treatment with PBS, LV-NC, or LV-CTRP12 for 72 h. A, B The expression of ABCA1 and ABCG1 was determined by qRT-PCR and western blot. C, D Detection of CD36 and SR-A expression using qRT-PCR and western blot. Data are expressed as the mean ± SD from three independent experiments. ****P < 0.0001; ns not significant.

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