Fig. 2: CircSPI1 is specifically upregulated in AML. | Cell Death & Disease

Fig. 2: CircSPI1 is specifically upregulated in AML.

From: CircSPI1 acts as an oncogene in acute myeloid leukemia through antagonizing SPI1 and interacting with microRNAs

Fig. 2

A The relative expression levels of circSPI1 and linear SPI1 in AML patients (N = 62) and healthy normal subjects (N = 8). B The expression levels of circSPI1 (left panel) and linear SPI1 (right panel) in AML patients with different karyotypes. Ribo-zero RNA-sequencing data of 48 AML samples with normal karyotype, including 5 APL patients, 4 t(8; 21) translocation, 3 inv(16), 2 inv(3), and 8 normal individuals, were retrieved and analyzed. *P < 0.05, **P < 0.01.

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