Fig. 5: p38α inhibition downregulates CRC-SC markers in an in vivo model.

A Mice treatment scheme. B Hematoxylin and eosin staining of AOM-treated APCMin/+ mice injected with the p38α inhibitor SB202190 or DMSO. Original magnification: 200x. C Immunohistochemistry analysis of colon tissue sections from C57BL/6 and AOM-treated APCMin/+ mice injected with the p38α inhibitor SB202190 or DMSO. Original magnification: 100x.