Fig. 5: GC7 modulates glucose flux in PCT cells.
From: Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney
Confluent PCT cells were treated or not with 30 µM GC7 for 24 h and then used for different analysis. a At the end of treatment cells were deprived in glucose and the efflux of glucose was measured in the next 8 h. Dots displayed mean ± SD of three independent experiments. b Western blot analysis of GLUT1 and GLUT2 expressions in membrane enriched protein lysate from PCT cells. β-Actin was used as loading control. MW molecular weight. *p < 0.05 evaluated using Mann–Whitney test.
