Fig. 2: Integrated analysis of the relationship between KIF18B expression and clinicopathological characteristics in PCa.
From: Kinesin family member 18B regulates the proliferation and invasion of human prostate cancer cells
A KIF18B expression in PCa and normal patient tissue samples from the TCGA dataset (normal, n = 52; tumor, n = 497). B KIF18B expression in PCa according to the Gleason score (normal, n = 52; score 6, n = 45; score 7, n = 247; score 8, n = 64; score 9, n = 136; score 10, n = 4). P < 0.001 for the following comparisons: normal vs Gleason score 7, normal vs score 8, normal vs score 9, score 6 vs score 7, score 6 vs score 8, score 6 vs score 9, score 7 vs score 8, and score 7 vs score 9. C Cancer-free survival analysis of patients in the TCGA dataset according to KIF18B mRNA expression level (high, n = 244; low, n = 242). D–F Biochemical recurrence-free survival analysis of patients stratified by D KIF18B expression (negative, n = 165; positive, n = 324), E positive surgical margin status (no, n = 450; yes, n = 39), and F Gleason score (<7, n = 180; 7, n = 219; >7, n = 90). Statistical analyses were performed by UALCAN (A, B) or the log-rank test (D–F). Boxplot data are presented as the median (Q1, Q3). ***P < 0.001.
