Fig. 5: KIF18B promotes migration and invasion and inhibits apoptosis of DU145 and PC-3 cells.
From: Kinesin family member 18B regulates the proliferation and invasion of human prostate cancer cells
A–D Transwell cell migration and invasion assays of KIF18B-overexpressing DU145 and PC-3 cells, and DU145 and PC-3 cells transfected with shCtrl, shKIF18B#1, or shKIF18B#2. E–F Statistical analysis of transwell cell migration and invasion ability of KIF18B-overexpressing DU145 and PC-3 cells, and DU145 and PC-3 cells transfected with shCtrl, shKIF18B#1, or shKIF18B#2. G PI and annexin V flow cytometric assay of apoptosis of DU145 and PC-3 cells transfected with shCtrl, shKIF18B#1, or shKIF18B#2. H, I Apoptotic rates of H DU145 cells and I PC-3 cells transfected with shCtrl, shKIF18B#1, or shKIF18B#2. Data are presented as the mean ± SD of at least three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001 by the Mann–Whitney U test or Student’s t test or one-way ANOVA.
