Fig. 7: KIF18B promotes PCa tumor growth in vivo.
From: Kinesin family member 18B regulates the proliferation and invasion of human prostate cancer cells
A Images of tumors formed from KIF18B-DU145 and Vector-DU145 cells. B Representative images of the fluorescence of live animals after injection of Vector-DU145 and KIF18B-DU145 cells. C, D Average C tumor weights (n = 16) and D tumor volumes (n = 16) from animals injected with Vector-DU145 and KIF18B-DU145 cells. E Total radiant efficiency of Vector-DU145 and KIF18B-DU145 groups (n = 16). F Immunohistochemical staining of Ki67, MMP-2, and p-AKT in tumors formed by Vector-DU145 and KIF18B-DU145 cells (n = 12). G Quantification of protein staining and TUNEL staining. H TUNEL assay on tumor tissues from nude mice (n = 12). Data are presented as the mean ± SD. Statistical analyses were performed with a t-test or t-test with Welch’s correction (*P < 0.05, **P < 0.01).
