Fig. 7: The circ-HMGA2/miR-1236-3p/ZEB1/EMT axis regulates LUAD cell metastasis. | Cell Death & Disease

Fig. 7: The circ-HMGA2/miR-1236-3p/ZEB1/EMT axis regulates LUAD cell metastasis.

From: Circ-HMGA2 (hsa_circ_0027446) promotes the metastasis and epithelial-mesenchymal transition of lung adenocarcinoma cells through the miR-1236-3p/ZEB1 axis

Fig. 7

Circ-HMGA2 is highly expressed in lung adenocarcinoma and acts as a sponge of miR-1236-3P to promote the expression of ZEB1. ZEB1 acts as a transcription factor of EMT, promoting the progression of EMT and the metastasis of lung adenocarcinoma.

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