Fig. 4: Proliferation and migration of melanoma cells was promoted by LINC00470 through enhancing APEX1. | Cell Death & Disease

Fig. 4: Proliferation and migration of melanoma cells was promoted by LINC00470 through enhancing APEX1.

From: LINC00470 accelerates the proliferation and metastasis of melanoma through promoting APEX1 expression

Fig. 4

A qRT-PCR analysis of APEX1 in cells transfected with OE-NC, OE-LINC00470, shNC, and shLINC00470, respectively. B Western blot analysis of APEX1 in cells transfected with OE-NC, OE-LINC00470, shNC, and shLINC00470, respectively. In the following experiments, all the cells were transfected with five different groups, including control, shNC, shLINC00470, shLINC00470 + OE-NC, and shLINC00470 + OE-APEX1, respectively. C, D The cell proliferation of cells with different treatments analyzed by MTT assay for 24, 48, and 72 h. E, F The colony formation assay of the cells with different treatments. G, H Cell migration ability of cells with different treatments analyzed by transwell assay. The mean ± SD in the graph shows the relative levels from three replicates. *p < 0.05, **p < 0.01.

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