Fig. 3: Liver-specific overexpression of FTO alleviates liver oxidative stress and mitochondrial fragmentation in vivo. | Cell Death & Disease

Fig. 3: Liver-specific overexpression of FTO alleviates liver oxidative stress and mitochondrial fragmentation in vivo.

From: N6-methyladenosine demethylase FTO impairs hepatic ischemia–reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation

Fig. 3

A–D Tissue levels of GSH, GSH-Px, SOD, and MDA were detected using ELISA at indicated time points after reperfusion. E Representative electron microscope photos of the mitochondria in the hepatic tissues infected with control AAV8-TBG-null and AAV8-TBG-FTO during IRI. N = 5; *P < 0.05 vs. AAV8-TBG-NC group.

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