Fig. 7: Drp1 contributes to the protective effect of FTO against HIRI. | Cell Death & Disease

Fig. 7: Drp1 contributes to the protective effect of FTO against HIRI.

From: N6-methyladenosine demethylase FTO impairs hepatic ischemia–reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation

Fig. 7

A Representative histopathologic images of liver sections harvested at 24 h after reperfusion (H&E staining; scale bars, 100 μm). The damage degree was graded using Suzuki criteria. B Blood samples were collected to determine the ALT and AST levels (U/L). C–F Tissue levels of GSH, GSH-Px, SOD, and MDA were detected using ELISA at indicated time points after reperfusion. N = 5; *P < 0.05 vs. indicated group.

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