Fig. 3: Downstream molecular of ADAMTS9 in GC were identified by using the RNA-sequencing method. | Cell Death & Disease

Fig. 3: Downstream molecular of ADAMTS9 in GC were identified by using the RNA-sequencing method.

From: DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells

Fig. 3

A ADAMTS9 is enriched in the nuclei of gastric mucosal cells. B, C The volcano plots and KEGG enrichment plots were generated from mRNA sequencing analysis of ADAMTS9-overexpressing BGC-823 cells and control cells transfected with empty plasmid. D, E Downstream potent molecular events were identified for impairing viability, proliferation, and motile capacity. F The downstream DEGs were validated by the qPCR in AGS and BGC-823 cells.

Back to article page