Table 1 Univariate and multivariate Cox proportional hazard models for overall survival of gastric cancer patients.

From: DNMT3A-mediated silence in ADAMTS9 expression is restored by RNF180 to inhibit viability and motility in gastric cancer cells

Predictor

Univariate analysis

Multivariate analysis

AIC

BIC

HR(95% CI)

P

HR (95% CI)

P

Gender

Female vs male

1.372 (0.905–2.079)

0.136

    

Age

≥60 vs <60

1.514 (1.012–2.245)

0.039*

1.528 (1.005–2.323)

0.047*

74.730

91.889

Tumor size

≥5 cm vs <5 cm

1.888 (1.250–2.851)

0.003**

1.591 (1.041–2.430)

0.032*

72.686

89.844

Tmuor location

Middle 1/3 vs up 1/3

1.232 (0.588–2.584)

0.580

    

Low 1.3 vs up 1/3

0.948 (0.545–1.649)

0.851

    

>2/3 stomach vs up 1/3

1.235 (0.661–2.307)

0.508

    

Lauren type

Diffuse vs intestinal

1.144 (0.677–1.934)

0.615

    

Mixed vs intestinal

1.621 (0.637–4.123)

0.311

    

Borrmann type

II vs I

0.552 (0.073–4.173)

0.565

    

III vs I

0.385 (0.052–2.847)

0.350

    

IV vs I

0.512 (0.064–4.113)

0.529

    

pT stage

pT3 vs pT2

0.547 (0.164–1.821)

0.326

    

pT4 vs pT2

0.788 (0.381–1.628)

0.519

    

pN stage

pN1c vs pN0

0.958 (0.397–2.315)

0.925

0.784 (0.319–1.929)

0.597

81.240

92.680

pN2 vs pN0

1.745 (0.911–3.341)

0.093

1.480 (0.758–2.889)

0.251

  

pN3 vs pN0

2.828 (1.638–4.883)

<0.001***

2.231 (1.273–3.912)

0.005**

  

Expression of ADAMTS9

Low vs high

1.732 (1.166–2.573)

0.009**

1.602 (1.069–2.399)

0.022*

71.555

88.714

  1. AIC akaike information criterion, BIC Bayesian information criterion.
  2. *P < 0.05; **P < 0.01; ***P < 0.001.
Back to article page