Fig. 2: CBLB induces a remote IL-22 release that triggers hepatic STAT3 signaling. | Cell Death & Disease

Fig. 2: CBLB induces a remote IL-22 release that triggers hepatic STAT3 signaling.

From: Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury

Fig. 2

A Western blot analysis of liver STAT3 and STAT3 phosphorylated at tyrosine 705 at control, 2 h, and 6 h following CBLB injection, and its STAT3 phosphorylated at tyrosine 705/STAT3 ratio, n = 3 mice per group. B Analysis of mouse serum 2 h post-CBLB injection, n = 7 mice. C IL-22 serum levels in WT and MyD88/Trif double knockout mice 2 h post-CBLB injection, n = 4 mice per group. D RNA expression in various tissue 2 and 6 h post-CBLB injection, n = 3 mice per group.

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