Fig. 3: DEGs in hESCs after knockdown of ATF3 during in vitro decidualization. | Cell Death & Disease

Fig. 3: DEGs in hESCs after knockdown of ATF3 during in vitro decidualization.

From: ATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients

Fig. 3

A Heat map showing hierarchical clustering of gene expression in decidualization and knockdown of the ATF3 group. B, C KEGG pathway enrichment analysis and GO analysis of the DEGs. D The DEGs related to the altered KEGG pathways. E GSEA results showed that the FoxO-targeted gene term was downregulated when ATF3 was silenced. F The relative expression of FoxO1 target genes, such as PRL, IGFBP-1, DCN, and LEFTY2.

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