Table 1 Relationship between HIF-1α, NRP1 and the clinicopathological features in Lung adenocarcinoma.

From: HIF-1α promoted vasculogenic mimicry formation in lung adenocarcinoma through NRP1 upregulation in the hypoxic tumor microenvironment

Variants

HIF-1α

χ2

p value

NRP1

χ2

p value

 

−

+

  

−

+

  

Sex

Male

40

53

2.004

0.157

43

50

0.684

0.408

Female

41

35

  

40

36

  

Age (years)

<65

46

62

3.414

0.065

53

55

0

0.989

≥65

35

26

  

30

31

  

Tumor size (cm)

<5

60

59

1

0.317

64

55

3.509

0.061

≥5

21

29

  

19

31

  

Grade

I + II

57

57

0.602

0.438

56

58

0.03

0.864

III + IV

24

31

  

27

28

  

Metastasis

No

66

58

5.235

0.022

67

57

5.173

0.025

Yes

15

30

  

16

29

  

VM

No

72

65

6.203

0.013

73

64

4.315

0.038

Yes

9

23

  

10

22

  
  1. P < 0.05 was statistically significant.
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