Fig. 3: MDSCs activate dormant cell growth. | Cell Death & Disease

Fig. 3: MDSCs activate dormant cell growth.

From: Inhibition of CCL7 derived from Mo-MDSCs prevents metastatic progression from latency in colorectal cancer

Fig. 3

A CD133, SOX2, c-Myc, and Cyclin D1 protein expressions in micro-metastatic cells or vitro-induced-dormant cell co-cultured with different numbers of MDSCs was detected by western blot. B Vitro-induced-dormant cells proliferation with different numbers of MDSCs co-culture were detected by CCK-8. C Vitro-induced-dormant cells proliferation with Mo-MDSCs or PMN-MDSCs co-culture were detected by CCK-8. D CD133, SOX2, c-Myc, and Cyclin D1 protein expressions in vitro-induced-dormant cells with Mo-MDSCs or PMN-MDSCs co-culture were detected by western blot. E IFN-γ in CD8+ T cells with Mo-MDSCs or PMN-MDSCs co-culture were detected by Flow cytometry. F Effect of Mo-MDSCs on promoting HT29 cells metastasis in vivo.

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