Fig. 5: USP7 activates the BCR-ABL signaling pathway in CML cells.
From: Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis
A K562 and KBM5 cells were infected with USP7 lentivirus for 96 h before being collected for WB assays against specific proteins as indicated. B, C K562 and KBM5 cells were treated with P5091 for 24 h, followed by WB assays as indicated. D K562 and KBM5 cells were infected with sgUSP7 lentivirus for 96 h before being collected for WB assays against indicated proteins.
