Fig. 1: miR-135b is elevated and associated with poor prognosis of patients in NSCLC. | Cell Death & Disease

Fig. 1: miR-135b is elevated and associated with poor prognosis of patients in NSCLC.

From: STAT3/miR-135b/NF-κB axis confers aggressiveness and unfavorable prognosis in non-small-cell lung cancer

Fig. 1

A Volcano plots analyzing differential expressions of miRNAs in LUAD and LUSC datasets from the TCGA database. B Analysis of the expression of miR-135b in NSCLC dataset from the NCBI/GEO database. C Real-time PCR analysis of miR-135b level in lung epithelial cell line, Beas-2B, and NSCLC cell lines. Error bars represent the mean ± SD obtained from three independent experiments. p values are calculated by a two-tailed, unpaired t-test. **p < 0.01; ***p < 0.001. D Representative photographs of in situ hybridization staining of miR-135b in NSCLC tissues. Original magnification: Upper, ×200; Lower, ×400. E Kaplan–Meier analysis of overall survival (OS) in 128 NSCLC patients.

Back to article page