Fig. 1: Expression levels of APE1 are positively correlated with NSCLC.

a, b Statistical analysis of APE1 mRNA expression levels in LUAD and LUSC from the TCGA database. c APE1 protein levels in normal lung HELF cell, NSCLC cell lines A549, NCI-H460, and NCI-H1299. d Immunohistochemical staining of APE1 in labeled normal lung tissues or tumor tissues. e Colony-formation assay in control or APE1-KD A549 and NCI-H460 cells. Representative images from one of three experiments are shown. Data are shown as the mean ± SD of three independent experiments. ***p < 0.001.