Fig. 5: HDAC6 regulates the proliferation of primordial follicle granulosa cell.
From: HDAC6 regulates primordial follicle activation through mTOR signaling pathway

A The western blotting results showed PCNA was increased after 2 dpp ovaries was cultured with TubA for 1 day. B Immunostaining stain of PCNA results showed that the growth of pfGCs in primordial follicles was increased compared with the control after 2 dpp ovaries were cultured with or without TubA for 1 day. C PCNA counting results showed that PCNA positive signaling was increased in pfGCs after with TubA compared with the control. The experiments were repeated at least three times. And representative images are shown. Scale bars: 50 μm.