Fig. 3: Clobetasol modifies spinal cord metabolism and relevant neurotransmitters. | Cell Death & Disease

Fig. 3: Clobetasol modifies spinal cord metabolism and relevant neurotransmitters.

From: Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing

Fig. 3

a and b Summary plot for pathway analysis (a) and quantitative enrichment analysis (b) for metabolites levels in CTB-Sap vehicle versus CTB-Sap clobetasol; c Schematic representation of amino acids biosynthesis showing significantly upregulated (green) and downregulated (red) metabolites in CTB-Sap clobetasol versus CTB-Sap vehicle group. d Metabolites levels in the spinal cord of HC, CTB-Sap vehicle and CTB-Sap clobetasol mice; data are shown as mean ± SEM and scattered dot plots of n = 4 mice per group; *p-value < 0.05, **p-value < 0.01, ****p-value < 0.0001 versus HC or between groups; one-way ANOVA.

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