Fig. 1: CircRNA circSLIT2 was upregulated in PDAC tissue and cells. | Cell Death & Disease

Fig. 1: CircRNA circSLIT2 was upregulated in PDAC tissue and cells.

From: Novel circular RNA circSLIT2 facilitates the aerobic glycolysis of pancreatic ductal adenocarcinoma via miR-510-5p/c-Myc/LDHA axis

Fig. 1

A A novel circRNA circSLIT2 (hsa_circ_0009113) was generated from the exon 4 to exon 2 with 216 spliced length. B Sanger sequencing demonstrated the full length of circSLIT2 and the conjunction sites of exon 4 and exon 2. C Venn diagram showed the candidate circRNAs from the circBase (http://www.circbase.org/), CircInteractome (https://circinteractome.nia.nih.gov/) and CircNet (http://syslab5.nchu.edu.tw/CircNet/). D The dysregulated circRNA expression profiles in the PDAC tissue and normal tissue were analyzed using GEO dataset (GSE69362). E Kaplan–Meier survival curves and log-rank test were performed to evaluate the survival of PDAC individuals with high or low circSLIT2 expression. F RT-qPCR illustrated the circSLIT2 expression in the PDAC specimens and normal specimens. G RT-qPCR illustrated the circSLIT2 expression in PDAC cell lines.

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