Fig. 3: CircSLIT2 regulated the proliferation and tumor growth of PDAC cells. | Cell Death & Disease

Fig. 3: CircSLIT2 regulated the proliferation and tumor growth of PDAC cells.

From: Novel circular RNA circSLIT2 facilitates the aerobic glycolysis of pancreatic ductal adenocarcinoma via miR-510-5p/c-Myc/LDHA axis

Fig. 3

A CCK-8 assay indicated the proliferation of Capan-2 cells transfected with circSLIT2 overexpression and PANC-1 cells transfected with circSLIT2 knockdown. B Flow cytometric for the cycle analysis demonstrated the cycle progression or cycle arrest at G0/G1 phase in Capan-2 or PANC-1 cells. In vivo mice xenograft assay showed that circSLIT2 knockdown in PANC-1 cells inhibited the tumor growth weight (C) and volume (D) of PANC-1 cells. **p < 0.01.

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