Fig. 6: CT45A1 activates β-catenin through participating in formation of the transcriptional complex of β-catenin.
From: CT45A1 promotes the metastasis of osteosarcoma cells in vitro and in vivo through β-catenin

A Western blotting for the quantification of c-Myc and CyclinD1 protein expressions in osteosarcoma cell lines. B qRT-PCR for the quantification of c-Myc and CyclinD1 protein expressions in osteosarcoma cell lines. C Co-IP analysis between CT45A1 and TCF4. D Co-IP analysis between CT45A1 and β-catenin. E Co-IP analysis between TCF4 and β-catenin under the condition of CT45A1 overexpression. F Co-IP analysis between CT45A1 and TCF4、β-catenin. **P < 0.01, compared to the control. The error bars indicate the means ± SDs.